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Encompassing Amino Acids: 19-174
Description: Human TREM2, also known as Triggering receptor expressed on myeloid cells 2 and Trem2a, GenBank Accession No. NM_018965, a.a. 19-174, fused at the C-terminus to the Fc portion of Human IgG1 and with a C-terminal Avi-tag, expressed in a Hek293 expression system. This protein was biotinylated using AviTag™ technology. MW=46 kDa.
Format: Aqueous buffer solution.
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_018965
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc-Avi-tag
Uniprot: Q9NZC2
Warnings: Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended. If necessary, use carrier protein (BSA 0.1 - 0.5%).
Biosafety Level: Not applicable (BSL-1)
References: 1. Guerreiro, R., et al., New England Journal of Medicine. 2013; 368: 1171272. Jonsson, T., et al., New England Journal of Medicine. 2013; 368: 107116