TRPC5 Antibody, Clone N67/15: PerCP

Mouse Anti-Human TrpC5 Monoclonal IgG2b

Target: TRPC5

Conjugate: PerCP

Product Type: Monoclonal

Clone Number: N67/15 (Formerly sold as S67-15)

Immunogen: Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5)

Swiss-Prot: Q9UL62

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~110kDa.

Cellular Localization: Membrane

Scientific Background: Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homo-multimeric TRPC5 and hetero-multimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin (1). This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as chloroform, halothane and propofol (2).

References: 1. Xu S.Z., et al. (2008) Nature 451(7174): 69-72.2. Bahnasi Y.M., et al. (2008) Br J. Pharamcol. 153(7): 1505-1512.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-344D-PCP
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-344D-PCP
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, Immunohistochemistry
• Isotyp: IgG2b
• Human Gene ID: 7224
• Wirt: Mouse