TRPV3 Antibody, Clone N15/39: PerCP

Mouse Anti-Rat TrpV3 Monoclonal IgG2a

Target: TRPV3

Conjugate: PerCP

Product Type: Monoclonal

Clone Number: N15/39 (Formerly sold as S15-39)

Immunogen: Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3

Swiss-Prot: Q4QYD9

Purification: Protein G Purified

Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~70kDa.

Cellular Localization: Membrane

Scientific Background: The TRPV3 protein belongs to a family of non-selective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermo sensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (1, 2).

References: 1. Masamoto Y., Kawabata F., Fushiki T. (2009) Biosci. Biotechnol. Biochem. 73(5): 1021-1027.2. Xiao R., et al. (2008) J Biol Chem. 283(10): 6162-6174.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-334D-PCP
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-334D-PCP
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2a
• Human Gene ID: 497948
• Wirt: Mouse