VDAC1 Antibody, Clone N152B/23: ATTO 488

Mouse Anti-Human VDAC1 Monoclonal IgG2a

Target: VDAC1

Conjugate: ATTO 488

Product Type: Monoclonal

Clone Number: N152B/23 (Formerly sold as S152B-23)

Immunogen: Fusion protein amino acids 1-283 (full-length) of human VDAC1. Mouse: 98% identity (279/283 amino acids identical). Rat: 98% identity (279/283 amino acids identical) >60% identity with VDAC2 and VDAC3.

Swiss-Prot: P21796

Purification: Protein G Purified

Storage Buffer: PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~30kDa. Does not cross-react with VDAC2 or VDAC3 (based on KO validation results).

Cellular Localization: Mitochondrion,Mitochondrion Outer Membrane,Cell Membrane

Scientific Background: Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-456D-A488
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-456D-A488
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2a
• Human Gene ID: 7416
• Wirt: Mouse