WDR45 Antibody: RPE

Rabbit Anti-Human WDR45 Polyclonal

Target: WDR45.

Conjugate: RPE .

Product Type: Polyclonal.

Immunogen: Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322).

Swiss-Prot: Q9Y484.

Purification: Peptide Affinity Purified.

Storage Buffer: PBS, 50% glycerol, 0.09% sodium azide.

Concentration: 1 mg/ml.

Specificity: Detects ~40 kDa.

Tissue Specificity: Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.

Scientific Background: WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.

References: 1. http://www.genecards.org/cgi-bin/carddisp.pl?gene=WDR45 2. Strausberg R.L., et al. (2002) Proc Natl Acad Sci U S A. 99(26): 16899–16903. 3. Haack T.B., et al. (2012) Am J Hum Genet. 91(6): 1144–1149.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSPC-651D-RPE
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SPC-651D-RPE
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Human Gene ID: 11152
• Wirt: Rabbit