Product Type: Inhibitor
CAS No.: 202475-60-3
MolecularFormula: C16H15N3O3
Molecular Weight: 297,3
Source: Synthetic
Purity: ≥98%
Solubility: Soluble in DMSO (~1 mg/ml), and DMF (~1 mg/ml)
Appearance: White to off-white solid
PubChem CID: 3794
Scientific Background: WHI P131 also known as Janex-1, is a reversible, potent, and specific inhibitor of JAK3. WHI P131 is cell permeable. It has been seen to inhibit glioblastoma cell adhesion and migration, as well as, thrombin-induced platelet aggregation.
References: 1. Sudbeck E.A., et al. (1999) Clin. Cancer Res: J. Am. Asso. Cancer Res. 5(6): 1569–1582.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.