Product Type: Inhibitor
CAS No.: 856243-80-6
MolecularFormula: C19H18BrN3O
Molecular Weight: 384,3
Source: Synthetic
Purity: >98%
Solubility: Soluble in 45 mg/ml DMSO, 25 mg/ml Ethanol
Appearance: Pale Yellow Solid
PubChem CID: 11222830
Scientific Background: A novel DUB inhibitor directly inhibiting USP9x, USP5, USP14 and UCH37 inducing rapid accumulation of polyubiquitinated proteins. Blocks Jak2 signaling via Jak2 ubiquitination.
References: 1. KapuriaV., et al. (2010) Cancer Res. 70: 9265.2. Kapuria V., et al. (2011) Cell Signal. 23: 2076.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.