ZM447439, CAS 331771-20-1

Aurora B kinase inhibitor

Product Type: Inhibitor

CAS No.: 331771-20-1

MolecularFormula: C29H31N5O4

Molecular Weight: 513,6

Source: Synthetic

Purity: ≥98% (TLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (50mg/mL)

Appearance: Orange solid

PubChem CID: 9914412

Scientific Background: ZM447439 is a potent and selective inhibitor of Aurora B kinase. ZM447439 induces cell growth arrest mid-way through mitosis, and therefore effectively activates apoptosis.

References: 1. Walsby E., Walsh V., Pepper C., Burnett A., & Mills K. (2008) Haematologica. 93(5): 662–669. 2. Kim K.W., et al. (2007) Int. J. Rad.Oncol. Biol. Phy. 67(5): 1519–1525.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-489-1MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-489-1MG
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK