Product Description: 1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2].
Applications: Neuroscience-Neuromodulation
Formula: C13H15NO
References: [1]Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9./[2]Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24.
CAS Number: 52438-21-8
Molecular Weight: 201.26
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: DNA/RNA Synthesis;Platelet-activating Factor Receptor (PAFR)
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