11β-Hydroxysteroid Dehydrogenase (Type 1) Polyclonal Antibody

Formulation: 500 µl of peptide affinity-purified polyclonal antibody

Immunogen: Synthetic peptide from the an internal region of human 11β-HSD1

Purity: ≥98%

Shelf life (days): 1095

Notes: 11β-Hydroxysteroid dehydrogenase (Type 1) (11β-HSD1) catalyzes the conversion of inactive cortisone to active cortisol in adipose tissue. mRNA and protein for this enzyme have been detected in a wide range of tissues including liver, kidney, testis, lung, heart, and colon.{12000} The enzyme’s expression is developmentally regulated, suggesting its importance in regulation of glucocorticoid action during embryonic development.{11999} Over-expression of 11β-HSD1 results in visceral obesity and metabolic syndrome including insulin-resistant diabetes, hyperlipidemia, and hyperphagia.{9545} Cayman’s 11β-HSD1 Polyclonal Antibody detects a 32 kDa protein in human, mouse, and rat liver samples by western blot analysis. The antibody can be used on paraffin-embedded tissue sections to detect 11β-HSD1 expression.

• Artikelnummer: CAY10004303-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10004303-500
• Green Labware: Nein
• Verpackungseinheit: 1 ea (500 µl)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting, Immunohistochemistry
• Wirt: Rabbit