2'-Deoxyadenosine-5'-O-diphosphoribose (sodium salt)

Formulation: A solid

Formal Name: 2′-deoxy-adenosine 5′-(trihydrogen diphosphate), P′→5-ester with D-ribose, disodium salt

Purity: ≥98%

Formula Markup: C15H21N5O13P2 • 2Na

Formula Weight: 587,3

Shelf life (days): 1460

Notes: 2'-Deoxyadenosine-5'-O-diphosphoribose is a transient receptor potential melastatin 2 (TRPM2) agonist.{51245} It increases calcium-induced currents in an inside-out patch clamp assay using HEK293 cells expressing human TRPM2 when used at a concentration of 30 µM. 2'-Deoxyadenosine-5'-O-diphosphoribose has been found in Jurkat cells. It is also a substrate of nucleotide triphosphate diphosphatase 9 (NUDT9), a mitochondrial enzyme involved in hydrolyzing pyrophosphates.{51246}

• Artikelnummer: CAY38356
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38356-500
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: Reinstoffe