Formulation: A solution in ethanol
Formal Name: 1,1′,1′′,1′′′-[1,4-piperazinediylbis(3,1-propanediylnitrilo)]tetrakis-2-dodecanol
Purity: ≥95%
Formula Markup: C58H120N4O4
Formula Weight: 937,6
Shelf life (days): 730
CAS Number: 2635329-26-7
Notes: 246C10 is an ionizable cationic lipid (pKa = 6.75).{66270} It has been used in combination with other lipids in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Intravenous administration of LNPs containing 246C10 and encapsulating an mRNA reporter selectively accumulate in mouse liver.