306-N16B, CAS 2803699-70-7

Formulation: A solution in ethanol

Formal Name: 3,3',3'',3'''-(((methylazanediyl)bis(propane-3,1-diyl))bis(azanetriyl))tetrakis(N-(2-(dodecyldisulfaneyl)ethyl)propanamide)

Purity: ≥98%

Formula Markup: C75H151N7O4S8

Formula Weight: 1471,6

Shelf life (days): 1095

CAS Number: 2803699-70-7

Notes: 306-N16B is an ionizable cationic lipid.{65938} It has been used in the generation of lipid nanoparticles (LNPs). Intravenous administration of LNPs containing 306-N16B and encapsulating an mRNA reporter accumulate specifically in the mouse lung primarily in lung endothelial cells. LNPs containing both 306-N16B and 306-O12B (Item No. 37549) and encapsulating mRNA encoding tuberous sclerosis complex 2 (Tsc2), a tumor suppressor, reduce tumor growth in a mouse model of pulmonary lymphangioleiomyomatosis (LAM) induced by intravenous injection of Tsc2-null kidney-derived epithelial tumor cells (TTJ cells).

• Artikelnummer: CAY37927-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37927-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK