3CL Protease, Untagged (SARS-CoV-2) Assay Kit

Products from BPS Bioscience require a minimum order value above 400€

Applications: Great for studying enzyme kinetics and HTS applications.

Background: Coronaviruses (CoVs) primarily cause multiple respiratory and intestinal infections in humans and animals. CoVs may enter into the cells with the help of proteases such as Severe Acute Respiratory Syndrome Coronavirus 3C-like protease (SARS-CoV-1 3CL Protease). The 3CL protease, also known as Main Protease (Mpro), plays a vital role in processing the polyproteins that are translated from the viral RNA 3CL Protease inhibitors that can block viral replication are promising potential drug candidates that could be used to treat patients suffering with the coronavirus infection.

Description: The 3CL Protease Assay Kit is designed to measure 3CL Protease sactivity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.

Storage Stability: At least one year from date of receipt when stored as directed.

Supplied As: The kit comes in a convenient 384-well format, with purified untagged 3CL Protease, fluorogenic substrate, and 3CL Protease assay buffer for 400 enzyme reactions. 3CL inhibitor GC376 is also included as a positive control.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Jared S. Morse, et al., 2020 Chem.Bio.Chem. 21:730-738.
2. Zhang, L., et al. 2020, Science 368 (6489): 409-412. 

• Artikelnummer: BPS78042-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 78042-2
• Green Labware: Nein
• Verpackungseinheit: 384 rxns.
• Mengeneinheit: PAK