Formulation: A crystalline solid
Formal Name: 1-(4-hydroxy-3-methoxyphenyl)-3-decanone
Purity: ≥98%
Formula Markup: C17H26O3
Formula Weight: 278,4
Shelf life (days): 1460
CAS Number: 27113-22-0
Notes: 6-Paradol is a phenolic ketone that has been found in ginger (Z. officinale) and has diverse biological activities, including antioxidant, anti-inflammatory, and anti-hyperglycemic properties.{50301,50302,50303} It inhibits hydrogen peroxide-induced oxidation of cell-free calf thymus DNA when used at a concentration of 100 μM.{50301} In vitro, 6-paradol (10 μg/ml) inhibits LPS-induced nitric oxide (NO), IL-6, and TNF-α production by mouse BV-2 microglia.{50302} In vivo, 6-paradol (6.75 mg/kg per day) lowers blood glucose levels in an oral glucose tolerance test (OGTT) and inhibits weight-gain in a mouse model of high-fat diet-induced obesity.{50303}
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