6-Thioguanosine-5'-O-diphosphate (sodium salt)

Formulation: A solution in water

Formal Name: 6-thio-guanosine 5′-(trihydrogen diphosphate), trisodium salt

Purity: ≥95%

Formula Markup: C10H12N5O10P2S • 3Na

Formula Weight: 525,2

Shelf life (days): 730

Notes: 6-Thioguanosine-5'-O-diphosphate is an inactive metabolite of the purine analog 6-thioguanine (Item No. 15774) and the immunosuppressive purine analog azathioprine (Item No. 13987).{51291,51292} It is formed from 6-thioguanine via a 6-thioguanosine monophosphate intermediate by phosphorylation and from azathioprine via 6-mercaptopurine (Item No. 23675) and other intermediates by a non-enzymatic process and several enzymatic reactions. Elevated blood levels of 6-thioguanosine-5'-O-diphosphate in patients with Crohn's disease correlate with a lower response rate to azathioprine.{51292}

• Artikelnummer: CAY38389
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38389-2.3
• Verpackungseinheit: 2.3 mg
• Mengeneinheit: STK
• Methode: Reinstoffe