6β-Naltrexol (CRM), CAS 49625-89-0

Formulation: A 1 mg/ml solution in methanol

Formal Name: (5α,6β)-17-(cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol

Formula Markup: C20H25NO4

Formula Weight: 343,4

Shelf life (days): 730

CAS Number: 49625-89-0

Notes: 6β-Naltrexol (Item No. 18790) is a certified reference material that is structurally categorized as an opioid. It is the major metabolite of naltrexone (Item Nos. ISO60192 / 15520).{32375} Unlike naltrexone, which acts as a µ-receptor antagonist or inverse agonist, 6β-naltrexol is a neutral opioid antagonist.{32377} 6β-Naltrexol binds the µ-opioid receptor more potently than naloxone (Item Nos. ISO60191 / 15594) or naltrexone (Kis = 94, 420, and 265 pM, respectively) but is ~100-fold less effective at blocking morphine-modulated pain in vivo, as assessed using the mouse hot plate test.{32376} This product is intended for research and forensic applications.

• Artikelnummer: CAY18790
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18790-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe, Isotopenmarkierung