Solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
Appearance: Off-white solid
PubChem CID: 54708532
Scientific Background: A 769662 is a potent and reversible activator of AMP-activated protein kinase (AMPK). It has been shown to inhibit fatty acid synthesis and decreases plasma glucose and triglyceride levels in vivo.
References: 1. Sanders M.J., et al. (2007) J. Biol. Chem. 282(45): 32539–32548. 2. Göransson O., et al. (2007) J. Biol. Chem. 282(45): 32549–32560.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.