α-Humulene, CAS 6753-98-6

Formulation: A neat oil

Formal Name: 2,6,6,9-tetramethyl-1E,4E,8E-cycloundecatriene

Purity: ≥95%

Formula Markup: C15H24

Formula Weight: 204,4

Shelf life (days): 1460

CAS Number: 6753-98-6

Notes: α-Humulene is a sesquiterpene that has been found in C. sativa, C. indica, and hemp with diverse biological activities.{41453,39866,39867,39868,39869} It is lethal to A. subpictus, A. albopictus, and C. tritaeniorhynchus mosquito larvae (LC50s = 6.19, 7.39, and 12.05 mg/ml, respectively).{39866} α-Humulene reduces growth of MCF-7 breast cancer cells by approximately 50% when used at a concentration of 32 mg/ml.{39867} It also reduces viability of Caco-2 cells in a concentration-dependent manner (IC50 = 24.4 mg/ml) but has no effect on viability of rat hepatocytes.{39868} In vivo, α-humulene (50 mg/kg) reduces histamine-induced paw edema in mice as well as carrageenan-induced TNF-α and IL-1β production and paw edema in mice and rats.{39869} It also reduces carrageenan-induced production of prostaglandin E2 (PGE2) and expression of inducible nitric oxide synthase (iNOS) and COX-2 in rats.

• Artikelnummer: CAY21574-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21574-500
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK