A11 (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-α-glutamyl-L-tyrosyl-L-valyl-L-glutaminyl-L-threonyl-L-valyl-L-lysyl-L-seryl-L-seryl-L-lysyl-glycine, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C117H204N46O32 • XCF3COOH

Formula Weight: 2767,2

Shelf life (days): 1460

Notes: A11 is a cell-penetrating peptide composed of the HIV-1 Tat protein transduction domain linked to an 11-amino acid peptide corresponding to residues 20-30 of the annexin A1 N-terminus.{67535} It decreases annexin A1 binding to Eph receptor tyrosine kinase A2 (EphA2) and increases EphA2 ubiquitination in HK1 nasopharyngeal carcinoma (NPC) cells. A11 (10 µM) inhibits HK1 and 5-8F NPC cell proliferation, migration, and invasion. In vivo, A11 reduces tumor volume in 5-8F and HK1 NPC mouse xenograft models.

• Artikelnummer: CAY35653-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35653-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK