Abbreviation: ACE2
Target Synonym: ACE2;ACEH
Conjugation: Unconjugated
UNIProt ID: Q9BYF1
Background: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human ACE2
Dilution: WB 1:500-1:2000,IHC 1:50-1:200,IF 1:50-1:200