AChE antibody (HL1102)

AChE antibody (HL1102)
Artikelnummer
GTX636298-100
Verpackungseinheit
100 μl
Hersteller
GeneTex

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Clone Name: HL1102

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 68

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]

Uniprot ID: P22303

Antigen Species: Human

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human AChE. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: acetylcholinesterase (Cartwright blood group)
Mehr Informationen
Artikelnummer GTX636298-100
Hersteller GeneTex
Hersteller Artikelnummer GTX636298-100
Green Labware Nein
Verpackungseinheit 100 μl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus), Cat (Feline)
Klonalität Monoclonal
Methode Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry
Isotyp IgG
Human Gene ID 43
Wirt Rabbit
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