Activin A, Human/Mouse/Rat (HEK293)

Product Description: Activin A, a multifunctional cytokine, is a member of TGF-β superfamily. Activin A first binds to the type II activin receptors (ActIIRA or ActRIIB) on the member surface, and then recruits and phosphorylates type I activin receptors (ActRI). Activin A primarily signal through SMAD2/3 proteins to regulate a variety of functions, including inflammation, fibrosis, and tumorigenesis[1]. Activin A Protein, Human/Mouse/Rat (HEK293) is produced in HEK293 cells, and consists of 117 amino acids (G310-S426).

Formula: 3624(Gene_ID)P08476 (G311-S426)(Accession)

References: [1]Ge J, et al. Involvement of CHOP in activin A induced myeloma NS 1 cell apoptosis. Oncol Rep. 2019;42(6):2644-2654./[2]Enrrico Bloise, et al. Activin A in Mammalian Physiology. Physiol Rev. 2019 Jan 1;99(1):739-780./[3]N L Frigon Jr, et al. Regulation of globin gene expression in human K562 cells by recombinant activin A. Blood. 1992 Feb 1;79(3):765-72./[4]D D Wu, et al. Expression of the activin axis and neuronal rescue effects of recombinant activin A following hypoxic-ischemic brain injury in the infant rat. Brain Res. 1999 Jul 24;835(2):369-78./[5]B Attardi, et al. Rapid stimulatory effect of activin-A on messenger RNA encoding the follicle-stimulating hormone beta-subunit in rat pituitary cell cultures. Mol Endocrinol. 1990 May;4(5):721-6.

Molecular Weight: 13-15 kDa

Compound Purity: 98.0

Target: Organoid

• Artikelnummer: MEXHY-P70311-2UG
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P70311-2UG
• Green Labware: Nein
• Verpackungseinheit: 2 μg
• Mengeneinheit: STK