Description: ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 with an IC50 of 1.1 µM and can be used in studies about cartilage destruction in arthritis.
CAS Number: 929634-33-3
Formula: C16H11ClF3N3OS3
Molecular Weight: 449,92
References: Wylie JD, et al. Adamts5 (aggrecanase-2) is widely expressed in the mouse musculoskeletal system and is induced in specific regions of knee joint explants by inflammatory cytokines. J Orthop Res. 2012 Feb;30(2):226-33.