Target Synonym: ADRB2;ADRB2R;ADRBR;B2AR;BAR;BETA2AR
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunogen: A synthetic peptide of human ADRB2
Dilution: WB 1:500-1:2000
Calculated MW: 46kDa
Observed MW: 50-100KDa
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