Alkaline Phosphatase (Tissue Non-Specific) antibody (HL2003)

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Clone Name: HL2003

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 57

Specificity/Sensitivity: This antibody is specific for human ALPL protein, and it does not cross react with human ALPI, ALPP, and ALPG protein.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]

Uniprot ID: P05186

Antigen Species: Human

Immunogen: Recombinant fragment of Alkaline Phosphatase (Tissue Non-Specific).

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: alkaline phosphatase, biomineralization associated

• Artikelnummer: GTX637904-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX637904-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Dog (Canine)
• Klonalität: Recombinant
• Methode: Western Blotting
• Isotyp: IgG
• Human Gene ID: 249
• Wirt: Rabbit
• Konjugat: Unconjugated