ALS2 blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89837.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Concentration:

Background: The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Region Sequence: LKACYYQIQREKLN

Full Name: ALS2, alsin Rho guanine nucleotide exchange factor

• Artikelnummer: GTX89837-PEP-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX89837-PEP-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
• Methode: ELISA, Blocking, Affinity Purification
• Human Gene ID: 57679