Product Description: Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
Applications: Cancer-programmed cell death
Formula: C13H24ClNO9
References: [1]Markus Ribbert, et al. Self coupling recombinant antibody fusion proteins. WO2009013359A2./[2]David Margulies, et al. Fluorescent molecular sensor for targeting changes in protein surfaces, and methods of use thereof. WO2015166491A2.