English
Androgen Receptor antibody
Androgen Receptor antibody
Artikelnummer
GTX03929-100
Verpackungseinheit
100 μl
Hersteller
GeneTex
Verfügbarkeit:
wird geladen...
Preis wird geladen...
Application Note: WB: 1:300-1:5000. ICC/IF: 1:50-1:200. IHC-P: 1:200-1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 99
Form: Liquid
Buffer (with preservative): 0.01M TBS, 1% BSA, 50% Glycerol, 0.03% Proclin300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]
Uniprot ID: P10275
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide derived from human AR (825-919).
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: androgen receptor
Calculated MW: 99
Form: Liquid
Buffer (with preservative): 0.01M TBS, 1% BSA, 50% Glycerol, 0.03% Proclin300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]
Uniprot ID: P10275
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide derived from human AR (825-919).
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: androgen receptor
| Artikelnummer | GTX03929-100 |
|---|---|
| Hersteller | GeneTex |
| Hersteller Artikelnummer | GTX03929-100 |
| Green Labware | Nein |
| Verpackungseinheit | 100 μl |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine), Rat (Rattus), Pig (Porcine), Goat (Caprine) |
| Klonalität | Polyclonal |
| Methode | Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry |
| Isotyp | IgG |
| Human Gene ID | 367 |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
Verwandte Artikel
Markieren Sie die Artikel, um Sie dem Warenkorb hinzuzufügen oder
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
