Angiopoietin-like Protein-4, His Tag, human recombinant (rHuANGPTL-4-His)

Angiopoietin-like Protein-4, His Tag, human recombinant (rHuANGPTL-4-His)
Artikelnummer
BOL87332.10
Verpackungseinheit
10 µg
Hersteller
Biomol

Verfügbarkeit: wird geladen...
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Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 25000 D

Description: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation (By similarity). (www.uniprot.org) Produced in E.coli. Polypeptide containing 204 amino acid residues of the Human ANGPTL4 and 16 additional amino acid residues. Manufactured with N-terminal HisTag.
Mehr Informationen
Artikelnummer BOL87332.10
Hersteller Biomol
Hersteller Artikelnummer 87332.10
Green Labware Nein
Verpackungseinheit 10 µg
Mengeneinheit STK
Reaktivität Human
Wirt Escherichia Coli
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