Angiotensinogen antibody (034)

Clone Name: 34

Application Note: IHC-P: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 53

Specificity/Sensitivity: It has cross-reactivity with human SERPINA1 protein, human SERPINA3 protein, human SERPINA5 protein, human SERPINC1 protein, human SERPIND1 protein, human SERPINF2 protein, human SERPING1 protein, and human SERPINI1 protein in ELISA assay.

Form: Liquid

Buffer (with preservative): Filter-sterilized PBS, no preservative.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]

Uniprot ID: P01019

Antigen Species: Human

Immunogen: Recombinant Human Angiotensinogen protein, His tag (GTX01232-pro)

Purification: Purified by Protein A

Conjugation: Unconjugated

Full Name: angiotensinogen

• Artikelnummer: GTX02046-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02046-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 183
• Wirt: Rabbit