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Encompassing Amino Acids: ANG2 258-496 (end), COMP 28-72
Applications: Useful for the study of signaling pathways. Also useful for receptor binding studies, screening inhibitors, and selectivity profiling.
Description: Human angiopoietin 2 (ANGPT2), also known as ANG-2, GenBank Accession No. NM_001147, a.a. 258-496 (end), with N-terminal FLAG-tag and mouse Cartilage Oligomeric Matrix Protein (COMP), GenBank Accession No. NM_016685, a.a. 28-72, MW=33.4 kDa, expressed in a HEK293 cell expression system.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.05% Tween-20, 100 ng/µl FLAG peptide, 20% glycerol, and 1 mM DTT.
Genbank: NM_001147 (ANG2), NM_016685 (COMP)
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal FLAG-tag
Uniprot: O15123
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Fiedler, U., et al., J. Biol Chem. 2003 Jan 17;278(3):1721-17.
2. Yuan, H.T., et al., Mol Cell Biol. 2009 Apr;29(8):2011-22.