Anti-Avian influenza virus nucleoprotein (A65)

Anti-Avian influenza virus nucleoprotein [A65], Recombinant, IgG-Fc Fusion, Rabbit

CloneID: A65

Antigen Long Description: The original antibody was generated by immunizing alpacas with avian influenza virus nucleoprotein, creating the appropriate phage display library, and panning against the original target.

Buffer Composition: PBS only.

Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.

Uniprot Accession No.: P26056

Specificity Statement: This antibody is specific for the avian influenza virus nucleoprotein.

Application Notes (Clone): The binding specificity of the original camelid (alpaca) single-domain antibody (sdAb; VHH) was tested in an ELISA. This antibody was used to generate an anti-avian influenza nucleoprotein and anti-human IgA bi-specific construct together with Ab04649 [A8]. The bi-specific construct detected a range of influenza virus strains in ELISA, including low-virulence and vaccine strains. Namely, H1N1, H3N2, H5N3, H5N1 (LP), H7N3(LP), H8N4, H10N8, H11N6, H12N5, H2N2, H4N6, H5N9, H6N2, H7N7, H9N2, H10N7, H12N6, and H13N6. The bi-specific construct also exhibited a significantly prolonged stability in vivo in Balb/c mice compared to the sdAb version of the antibody (CN111116752B).

• Artikelnummer: ABAAb04650-23.159-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04650-23.159-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Virus
• Klonalität: Recombinant
• Methode: ELISA, In Vivo Assay
• Isotyp: IgG-Fc Fusion
• Wirt: Rabbit