Anti-CCP (AbAb01-CCP)

Anti-CCP [AbAb01-CCP], Recombinant, IgG2b kappa, Mouse

CloneID: AbAb01-CCP

Heavy Chain modification: Fc Silent™

Buffer Composition: PBS only.

Chimeric Use Statement: This is a reformatted mouse IgG2b Fc Silent™ antibody, based on the original mouse scFv format, created for improved compatibility with existing reagents, assays and techniques.

Specificity Statement: This antibody can detect cyclic citrullinated peptide (CCP), which is a serological marker for rheumatoid arthritis diagnosis. Citrulline is a nonstandard amino acid that is produced by diminution of arginine residue present on certain human proteins by the peptidyl arginine-deiminase (PAD) enzyme. The release of PAD from dying cells citrullinates extracellular proteins that contain arginine. Citrullination appears to be an inflammation-dependent process since it is present in many inflammatory tissues.

Application Notes (Clone): This antibody can be used for the detection of cyclic citrullinated peptides in a sample using ELISA (CN110272497).

• Artikelnummer: ABAAb04583-3.3-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04583-3.3-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: IgG2b kappa
• Wirt: Mouse