Anti-CCR2 Antibody Picoband™ (monoclonal, 8C4)

Clone Number: 8C4

Immunogen: E.coli-derived human CCR2 recombinant protein (Position: M1-F125).

Concentration: Adding 0.2 ml of distilled water =f 500 μg/ml.

Format: Lyophilized

Storage buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Additional info: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.Add 0.2ml of distilled water will yield a concentration of 500ug/ml. Background: C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. It is mapped to 3p21.31. The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. Subcellular Localization: Cell membrane. Multi-pass membrane protein. Tissue Specificity: Expressed by monocytes and IL2-activated NK cells.

• Artikelnummer: SANMON23717
• Hersteller: Sanbio / Monosan
• Hersteller Artikelnummer: MON23717
• Green Labware: Nein
• Verpackungseinheit: 100μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2b
• Wirt: Mouse