CloneID: GBR500 (Vatelizumab, TMC-2206)
Heavy Chain modification: Fc Silent™
Antigen Long Description: The parental mouse antibody was generated by immunizing BALB/c mice with human fibrosarcoma HT1080 cells. The original humanized version was generated by grafting the CDRs of murine parental antibody onto human acceptor framework regions.
Buffer Composition: PBS only.
Concentration: 1 mg/ml
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent Fc Silent™ antibody, based on the original human IgG4 format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P17301