Anti-FcGR3A (CD16A) IgG Antibody, Biotin-Labeled

Products from BPS Bioscience require a minimum order value above 400€

Applications: This product is for research use only.  It is not suitable for human, diagnostic, or therapeutic use.

Cross Reactivity: This antibody recognizes human FcGR3A/CD16A. It does not recognize human FcGR3B (CD16B). It has not been tested with other species

Description: This anti-FcGR3A (CD16A) antibody is a purified, biotinylated, recombinant human monoclonal antibody which recognizes the human FcGR3A/CD16A protein. Fc Gamma Receptor IIIa (FcGRIIIA; FcγRIIIA), also known as CD16a, is a low/intermediate affinity receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, antibody-dependent cytotoxicity, and clearance of immune complexes.  FcGR3A/CD16A plays a role in the activation of natural killer (NK) cells. Clinically, it serves as a marker of certain immune cells such as neutrophils. CD16 expression has been observed at the surface of T cells in patients with chronic viral infections (such as COVID-19). It is considered a potential therapeutic target to potentiate the efficacy of therapeutic antibodies used to treat solid tumors, or as direct target in hematopoietic cancers.This antibody has been tested for specific binding to purified human FcGR3A/CD16A (BPS Bioscience #79013) in an ELISA binding assay with colorimetric detection. It does not cross-react with purified human FcGR2B/CD16B.

Format: Aqueous buffer solution

Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Purification: Protein A affinity chromatography from HEK293 supernatants.

Purity: ≥90%

Storage Stability: At least 12 months at -80°C.

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

• Artikelnummer: BPS101225-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 101225-2
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Klonalität: Monoclonal
• Isotyp: IgG1