Anti-FGFR-1 (FR1-H7)

Anti-FGFR-1 [FR1-H7], Recombinant, Fab fragment kappa, Human

CloneID: FR1-H7

Heavy Chain modification: His-Tagged

Antigen Long Description: The original antibody was raised by panning a fab library against FGFR-1(IIIb).

Buffer Composition: PBS only.

Uniprot Accession No.: P11362

Specificity Statement: This antibody is specific for human FGFR-1(IIIb) and FGFR-1(IIIc).

Application Notes (Clone): The original antibody was used for a co-culture proliferation assay on HUVEC-Akt cells. It showed a decrease in cell proliferation (Ding et al., 2015; PMID:26116571). This antibody was used for an ELISA on FGFR-1. Here is showed binding to FGFR-1(IIIb) and FGFR-1(IIIc). This antibody was used for immunoprecipitation on FGFR-1. Where it showed similair results to the ELISA. This antibody was used in vivo on nude mice. The effect of the antibody was significant weight reduction within 48 hours (US8263074B2).

• Artikelnummer: ABAAb04597-10.29-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04597-10.29-BT
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Isotyp: Fab fragment kappa
• Wirt: Human