English
Anti-Flagellin protein (1E08)
Anti-Flagellin protein [1E08], Recombinant, IgG-Fc Fusion, Rabbit
Artikelnummer
ABAAb04632-23.159
Verpackungseinheit
100 μg
Hersteller
Absolute Antibody
Verfügbarkeit:
wird geladen...
Preis wird geladen...
CloneID: 1E08
Antigen Long Description: The original antibody was generated by immunizing alpacas with heat-inactivated Salmonella cells.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody is specific for the flagellin protein (FliC) of Salmonella enterica, which plays a pivotal role in bacterial motility and pathogenicity. FliC is the main structural component of the bacterial flagella in Salmonella enterica, tail-like structures essential for bacterial movement and invasion of host tissues. Targeting FliC can potentially neutralize the pathogen by hindering its motility, thus preventing its invasion of host cells. Additionally, antibodies against FliC may facilitate bacterial recognition and elimination by the host immune system, aiding in the clearance of the bacteria from the body.
Application Notes (Clone): The original version of this antibody (alpaca VHH) exhibited significant inhibition of bacterial motility and growth in S. enterica strain 4904. In motility assays, the antibody reduced the diameter of bacterial growth circles compared to controls. Furthermore, in cell proliferation assays, the antibody inhibited Salmonella growth, as indicated by reduced optical density at 600 nm after 18 hours of incubation (US10421806B2).
Antigen Long Description: The original antibody was generated by immunizing alpacas with heat-inactivated Salmonella cells.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody is specific for the flagellin protein (FliC) of Salmonella enterica, which plays a pivotal role in bacterial motility and pathogenicity. FliC is the main structural component of the bacterial flagella in Salmonella enterica, tail-like structures essential for bacterial movement and invasion of host tissues. Targeting FliC can potentially neutralize the pathogen by hindering its motility, thus preventing its invasion of host cells. Additionally, antibodies against FliC may facilitate bacterial recognition and elimination by the host immune system, aiding in the clearance of the bacteria from the body.
Application Notes (Clone): The original version of this antibody (alpaca VHH) exhibited significant inhibition of bacterial motility and growth in S. enterica strain 4904. In motility assays, the antibody reduced the diameter of bacterial growth circles compared to controls. Furthermore, in cell proliferation assays, the antibody inhibited Salmonella growth, as indicated by reduced optical density at 600 nm after 18 hours of incubation (US10421806B2).
| Artikelnummer | ABAAb04632-23.159 |
|---|---|
| Hersteller | Absolute Antibody |
| Hersteller Artikelnummer | Ab04632-23.159 |
| Verpackungseinheit | 100 μg |
| Mengeneinheit | STK |
| Reaktivität | Various species |
| Klonalität | Recombinant |
| Methode | ELISA, In Vivo Assay, Inhibition |
| Isotyp | IgG-Fc Fusion |
| Wirt | Rabbit |
| Produktinformation (PDF) |
|
| MSDS (PDF) | Download |
Verwandte Artikel
Markieren Sie die Artikel, um Sie dem Warenkorb hinzuzufügen oder
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
