Anti-IL-6 (2G9)

Anti-IL-6 [2G9], Recombinant, IgG2a kappa, Mouse

CloneID: 2G9

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was generated by immunizing New Zealand white rabbits with recombinant Mouse IL-6 protein (Uniprot ID:P08505).

Buffer Composition: PBS only.

Chimeric Use Statement: This is a reformatted mouse IgG2a Fc Silent™ antibody, based on the original mouse IgG format, created for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P08505

Specificity Statement: This antibody binds mouse IL-6, a cytokine found in fibroblasts, monocytes/macrophages, T lymphocytes, B lymphocytes and a variety of tumor cells. IL-6 plays an important role in immune response, hematopoiesis, inflammation and stress response.

Application Notes (Clone): This antibody binds mouse IL-6 with a binding affinity in the nanomolar range. This antibody was used as a labelling antibody in combination with 12E1 as a capture antibody for the development of a sandwich ELISA assay for detection of mouse IL-6. This antibody pair specifically recognized mouse IL-6 in samples with a sensitivity as low as 1.56pg/mL (CN116715763).

• Artikelnummer: ABAAb04657-2.3-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04657-2.3-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: IgG2a kappa
• Wirt: Mouse