Target: CD4
Clone: GK1.5
Specificity: Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) recognizes an epitope on Mouse CD4
Purification method: This monoclonal antibody was purified using Protein G
Antigen Distribution: The L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.
Background: CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.
Immunogen: Mouse CTL clone V4
Concentration: ≥ 2.0 mg/ml
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity: >95% by SDS-PAGE and HPLC
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Aggregation: Aggregation level ≤ 5%
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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