Anti-Mouse CD49d In Vivo Antibody (PS/2) - Low Endotoxin

Anti-Mouse CD49d In Vivo Antibody (PS/2) - Low Endotoxin, Host: Rat, Rat IgG2b kappa
Artikelnummer
ICH1200-100MG
Verpackungseinheit
100mg
Hersteller
Ichorbio

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Target: CD49d.

Clone: PS/2.

Specificity: PS/2 activity is directed against mouse CD49d and is cross reactive against human CD49d.

Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Antigen Distribution: CD49d is expressed on T cells, B cells, NK , dendritic cells, thymocytes, monocytes, eosinophils, mast cells.

Background: Hybridoma supernatants were screened by cell adhesion assay and cells producing blocking antibodies were cloned. Adhesion is blocked in a dose dependent manner when PS/2 is used with P815 and +/+ 2.4 stromal cells. 70Z/3 cells are also sensitive to PS/2 inhibition. PS/2 is known to block binding of CD49d to its ligands. Lymphocyte production is completely blocked when PS/2 is included in Whitlock-Witte culture.

Immunogen: PS/2 was generated by immunizing Fisher rats with P815 cells and subsequently fusing the spleen cells with Sp2/0.

Concentration: ≥ 2.0 mg/ml.

Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity: >95% by SDS-PAGE.

Endotoxin: <1.0 EU/mg as determined by the LAL method.

Aggregation: Aggregation level ≤ 5%.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Mehr Informationen
Artikelnummer ICH1200-100MG
Hersteller Ichorbio
Hersteller Artikelnummer ICH1200-100MG
Green Labware Nein
Verpackungseinheit 100mg
Mengeneinheit STK
Reaktivität Human, Mouse (Murine)
Klonalität Monoclonal
Methode Immunofluorescence, Flow Cytometry, Immunohistochemistry
Isotyp Rat IgG2b kappa
Wirt Rat
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