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Anti-Mouse CD54 In Vivo Antibody - Ultra Low Endotoxin (YN1/1.7.4)
Anti-Mouse CD54 In Vivo Antibody - Ultra Low Endotoxin (YN1/1.7.4), Host: Rat, Rat IgG2b κ
Artikelnummer
ICH1059UL-50MG
Verpackungseinheit
50mg
Hersteller
Ichorbio
Verfügbarkeit:
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Target: CD54.
Clone: YN1/1.7.4.
Specificity: Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) recognizes an epitope on Mouse ICAM-1.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Background: Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
Immunogen: Mouse NS-1 cells.
Concentration: 1.0 mg/ml.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity: >98% by SDS-PAGE and HPLC.
Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 1%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Clone: YN1/1.7.4.
Specificity: Anti-CD54 In Vivo Antibody - Low Endotoxin (YN1/1.7.4) recognizes an epitope on Mouse ICAM-1.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution: The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation.
Background: Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
Immunogen: Mouse NS-1 cells.
Concentration: 1.0 mg/ml.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Purity: >98% by SDS-PAGE and HPLC.
Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method.
Aggregation: Aggregation level ≤ 1%.
Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
| Artikelnummer | ICH1059UL-50MG |
|---|---|
| Hersteller | Ichorbio |
| Hersteller Artikelnummer | ICH1059UL-50MG |
| Green Labware | Nein |
| Verpackungseinheit | 50mg |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine) |
| Klonalität | Monoclonal |
| Methode | Immunohistochemistry (frozen), Immunoprecipitation, Western Blotting, Flow Cytometry, Functional Assay |
| Isotyp | Rat IgG2b κ |
| Wirt | Rat |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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