Anti-MuSK; (MuSK #13)

Anti-MuSK; [MuSK #13], Recombinant, IgG1 kappa, Human

CloneID: MuSK #13

Antigen Long Description: This antibody was raised by immunizing mice with human MuSK.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: O15146

Specificity Statement: This antibody is specific for human MuSK.

Application Notes (Clone): The original antibody was used in vitro to test if it could activate its target. It showed to be a potent MuSK activator. The antibody was also tested in vivo on mice. Here is was shown to localize to the neuromuscular junctions here it increased innervation. This antibody did not show any delay in onset of ALS symptoms (Sengupta-Ghosh et al., 2019; PMID:30528255).

• Artikelnummer: ABAAb04595-10.0
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04595-10.0
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: In Vivo Assay
• Isotyp: IgG1 kappa
• Wirt: Human