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Anti-Neurofibromin/NF1 Antibody Picoband™ (monoclonal, 4C6F10)
Anti-Neurofibromin/NF1 Antibody Picoband™ (monoclonal, 4C6F10)
Artikelnummer
SANMON23839
Verpackungseinheit
100μg
Hersteller
Sanbio / Monosan
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Clone Number: 4C6F10
Immunogen: E.coli-derived human Neurofibromin/NF1 recombinant protein (Position: R160-Q270).
Concentration: Adding 0.2 ml of distilled water =f 500 μg/ml.
Format: Lyophilized
Storage buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Additional info: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. Background: Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Subcellular Localization: Tissue Specificity:
Immunogen: E.coli-derived human Neurofibromin/NF1 recombinant protein (Position: R160-Q270).
Concentration: Adding 0.2 ml of distilled water =f 500 μg/ml.
Format: Lyophilized
Storage buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Additional info: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. Background: Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Subcellular Localization: Tissue Specificity:
| Artikelnummer | SANMON23839 |
|---|---|
| Hersteller | Sanbio / Monosan |
| Hersteller Artikelnummer | MON23839 |
| Verpackungseinheit | 100μg |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine), Rat (Rattus) |
| Klonalität | Monoclonal |
| Methode | Western Blotting, Flow Cytometry, Immunohistochemistry |
| Isotyp | IgG2b |
| Wirt | Mouse |
| Konjugat | Unconjugated |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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Gernot Ensinger, M.Sc.
Laurent Haze
