Anti-PspA (2B11)

Anti-PspA [2B11], Recombinant, IgG lambda, Rabbit

CloneID: 2B11

Antigen Long Description: The original antibody was selected from a synthetic human scFv library through biopanning against recombinant PspA.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: A0A1M4NIX2

Specificity Statement: This antibody is specific for the Streptococcus pneumoniae PspA. The epitope on PspA was defined to residues 231-242 by mutational analysis and supported by molecular docking analysis.

Application Notes (Clone): The dissociation constant (K_d) of the original human scFv version of this antibody was 5.3 ± 2.3 nM as measured in a biolayer interferometry assay. This antibody detected PspA in immunoblots; it exhibited a dose-dependent recognition of recombinant PspA with no cross-reactivity towards other tested pneumococcal antigens and also detected endogenous PspA from pneumococcal lysates (Jang et al., 2017; PMID: 27845043).

• Artikelnummer: ABAAb04716-23.0
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04716-23.0
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Various species
• Klonalität: Recombinant
• Methode: ELISA, Immunoblotting, BLI Binding Assay
• Isotyp: IgG lambda
• Wirt: Rabbit