Anti-TGFBR2 Antibody Picoband™ (monoclonal, 2F11)

Anti-TGFBR2 Antibody Picoband™ (monoclonal, 2F11)
Artikelnummer
SANMON23791
Verpackungseinheit
100μg
Hersteller
Sanbio / Monosan

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Clone Number: 2F11

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TGFBR2, different from the related mouse sequence by five amino acids, and from the related rat sequence by eight amino acids.

Concentration: Adding 0.2 ml of distilled water =f 500 μg/ml.

Format: Lyophilized

Storage buffer: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Additional info: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.Add 0.2ml of distilled water will yield a concentration of 500ug/ml. Background: TGFBR2 (transforming growth factor, beta receptor II (70/80kDa)), also known as TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II (TGF-beta receptor type II, TbetaR-II), is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encodes a deduced 565-amino acid protein with a calculated molecular mass of approximately 60 kD in length. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different informs have been characterized. Subcellular Localization: Tissue Specificity:
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Artikelnummer SANMON23791
Hersteller Sanbio / Monosan
Hersteller Artikelnummer MON23791
Verpackungseinheit 100μg
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunofluorescence, Western Blotting, Flow Cytometry, Immunohistochemistry, Immunocytochemistry
Isotyp IgG2b
Wirt Mouse
Konjugat Unconjugated
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