Apolipoprotein B antibody (HL1962)

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Clone Name: HL1962

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 516

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

Uniprot ID: P04114

Antigen Species: Human

Immunogen: Recombinant fragment of human Apolipoprotein B

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: apolipoprotein B

• Artikelnummer: GTX637799-S-25
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX637799-S-25
• Verpackungseinheit: 25 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, ELISA, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 338
• Wirt: Rabbit
• Konjugat: Unconjugated