Apolipoprotein B ELISA pair (LDL20/17/LDL11)

Calculated MW: 516

Form: Liquid

Concentration:

Background: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

Uniprot ID: P04114

Full Name: apolipoprotein B

• Artikelnummer: GTX03048-1
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX03048-1
• Green Labware: Nein
• Verpackungseinheit: 1 pair
• Mengeneinheit: STK
• Reaktivität: Human
• Methode: ELISA
• Human Gene ID: 338