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APP Polyclonal Antibody, Rabbit
APP Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92271-120
Verpackungseinheit
120 µl
Hersteller
Elabscience Biotechnology
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Abbreviation: APP
Target Synonym: AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2;Amyloid beta A4;APP;Aβ42;preA4
Conjugation: Unconjugated
UNIProt ID: P05067
Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human APP
Dilution: IF 1:50-1:200
Target Synonym: AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2;Amyloid beta A4;APP;Aβ42;preA4
Conjugation: Unconjugated
UNIProt ID: P05067
Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human APP
Dilution: IF 1:50-1:200
| Artikelnummer | ELSE-AB-92271-120 |
|---|---|
| Hersteller | Elabscience Biotechnology |
| Hersteller Artikelnummer | ELA-E-AB-92271-120 |
| Green Labware | Nein |
| Verpackungseinheit | 120 µl |
| Mengeneinheit | STK |
| Reaktivität | Human, Mouse (Murine) |
| Klonalität | Polyclonal |
| Methode | Immunofluorescence |
| Isotyp | IgG |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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